Laboratory of Molecular Biology and DNA Repair

July 09, 2018

First date today for young investigators in anti-cancer research with the training initiatives of PreCanMed, the cross border project on precision anti-cancer medicine funded by the European Union, within the Interreg Italia-Austria Programme 2014-2020. The secrets of one of the most advanced research technology and a fast-track to personalized approaches in medicine will be in the hands of the participants to the first Summer School on Tumor Organoids organized by PreCanMed in Innsbruck.

June 24, 2018

Also this year the Department of Medicine (University of Udine) has given high school students  the opportunity to get an overview of a certain scientific fields. Students were allowed to attend the Professor Tell's laboratory of molecular biology and DNA repair. The work experience has given them the possibility to practice team-work skills, to develop knowledges, to gain insight into a specific sector and to clarify their career goals. The study/work experience week tutored high school students bridge the gap between theory and practice by providing in site tours and opportunities to gain hands-on and practical experience with the University.

January 23, 2018

Associazione Italiana per la Ricerca sul Cancro (AIRC) uses its funds to support cancer research in Italy. AIRC's mission is to understand, prevent and cure cancer through research and outreach activities. AIRC has recently financed three research projects on cancer cells with 1.250.000 Euros. The new studies started in January are sustained for five years in order to develop new medicines for the treatment of tomours, making the diagnosis  even more precocious and enabling choice of personalised therapies. Those studies are based on a recent research published in the scientific journal Nature Communications carried out by the research team of  the Laboratory of Molecular Biology and DNA Repair.

October 17, 2017

Mammalian apurinic/apyrimidinic endonuclease 1 is a DNA repair enzyme involved in genome stability and expression of genes involved in oxidative stress responses, tumor progression and chemoresistance. However, the molecular mechanisms underlying the role of apurinic/apyrimidinic endonuclease 1 in these processes are still unclear. Recent findings point to a novel role of apurinic/apyrimidinic endonuclease 1 in RNA metabolism. Through the characterization of the interactomes of apurinic/apyrimidinic endonuclease 1 with RNA and other proteins, we demonstrate here a role for apurinic/apyrimidinic endonuclease 1 in pri-miRNA processing and stability via association with the DROSHA-processing complex during genotoxic stress.

May 29, 2017

The Italian-Austrian team of PreCanMed publicly present plans and perspectives of their research and innovation initiative against cancer at the first PreCanMed Workshop in Innsbruck today. Leading experts of this cross-border cooperation project will also discuss about the latest findings in cancer research with students, other scientists and clinicians, and with citizens. PreCanMed is a project funded by the European Union, European Regional Development Fund and Interreg V-A Italia-Austria 2014-2020