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RESEARCH ACTIONS
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Molecular Mechanisms involved in the maintenance of Genomic Stability (BER pathway) and its relevance in tumor biology
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Non-canonical roles of DNA-repair enzymes in cancer biology associated to RNA-metabolism and nc-RNA decay and stability
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Development of small molecules inhibitors of DNA repair enzymes for combination therapy of tumors
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Development of human organoids from Colon cancer specimens for Precision Medicine
MODELS
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BER enzymes (particularly APE1 and several DNA glycosylases)
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HCC cancer
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Breast cancer cell lines
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Lung cancer cell lines
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